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IMPACT® Peptide 1.5

IMPACT® Peptide 1.5

Peptide-based immunonutrition designed to promote tolerance in surgery and trauma patients. Contains a proven blend of arginine, fish oil and nucleotides supported by 40+ published RCTs and many real world evidence trials.

  • Only IMPACT® formulas contain a unique studied blend of L-arginine, omega-3 fatty acids and nucleotides*. Given as early enteral nutrition, this blend of immunonutrients supports the immune system and helps reduce rates of infection, length of stay and ventilator days in surgical and critically ill patients.1-3. These immunonutrients have also been found most efficacious for use in major cancer surgery.4
  • Contains immune-modulating ingredients supported for perioperative use by the Critical Care Nutrition Guidelines.5**
  • Shown in a retrospective study to be associated with lower adjusted mean hospital cost/day vs. lower arginine immunonutrition or standard high-protein formula.6
  • Hydrolyzed protein and 50% of fat as MCT helps facilitate absorption, which supports formula tolerance.7
  • High protein and supplemented with L-arginine, zinc and other antioxidants to support wound management.8

Impact® Peptide 1.5 Unflavored
kcal/mL 1.5
Caloric Distribution Protein (% of kcal)
 		Protein 25%
Carbohydrate 38%
Fat 37%
L-Arginine (g) 4.7
L-Glutamine (g)
Sodium (mEq) 13
Calcium (mEq) 13
Potassium (mEq) 12
Chloride (mEq) 12
NPC:N Ratio 62:1
MCT:LCT Ratio 50:50
n6:n3 Ratio 1.5:1
Free Water (%) 77
Dietary Nucleotides (g) 0.45*
EPA + DHA (g) 1.23
Source of Oil
Osmolality (mOsm/kg water) 510
Density (g/mL)
Renal Solute Load (mOsm/L)
mL to Meet 100% DRI
ARA (mg)
  • Patients at risk of infection associated with major elective surgery (upper GI, lower GI, bladder, gynecological oncology, head and neck, non-small cell lung cancer, cardiac and hernia)
  • Patients at risk of infection associated with trauma, traumatic brain injury, burns
  • Wounds and pressure injuries (Stages 2, 3, 4, unstageable)
  • Patients at risk of GI intolerance
  • Metabolic stress
  • Volume sensitivity
  • Increased caloric needs
  • Early enteral feeding
  • Transition from TPN

Important Notes:

NOT FOR PARENTERAL USE
This product is intended for use under medical supervision.
Suitable for use in adults.
Not indicated when immune suppression is desired.

  • Lactose intolerance*
  • Gluten-free

Important Notes:

*Not for individuals with galactosemia IMPACT® PEPTIDE 1.5 formula contains milk protein. Not appropriate for individuals with cow’s milk protein allergy.

  • Hydrolyzed Casein (Milk)
  • L-Arginine
  • Medium Chain Triglycerides
  • Refined Fish Oil (Anchovy, Sardine)
  • Soybean Oil
  • Maltodextrin
  • Cornstarch
WATER, MALTODEXTRIN, ENZYMATICALLY HYDROLYZED CASEIN (MILK), MEDIUM CHAIN TRIGLYCERIDES, AND LESS THAN 2% OF L-ARGININE, CORNSTRACH, REFINED FISH OIL (ANCHOVY, SARDINE), SOYBEAN OIL, CITRIC ACID, CALCIUM CITRATE, RNA SALT, MAGNESIUM CHLORIDE, POTASSIUM PHOSPHATE, ASCORBIC ACID, SALT, SOY LECITHIN, SODIUM CITRATE, CHOLINE CHLORIDE, GUAR GUM, XANTHAN GUM, POTASSIUM CITRATE, TAURINE, MAGNESIUM OXIDE, SODIUM ASCORBATE, L-CARNITINE, DL-ALPHA TOCOPHERYL ACETATE, ZINC SULFATE, FERROUS SULFATE, NIACINAMIDE, CALCIUM PANTOTHENATE, MANGANESE SULFATE, COPPER SULFATE, PYRIDOXINE HYDROCHLORIDE, BETA-CAROTENE, THIAMINE MONONITRATE, VITAMIN A PALMITATE, RIBOFLAVIN, FOLIC ACID, BIOTIN, SODIUM MOLYBDATE, CHROMIUM CHLORIDE, POTASSIUM IODIDE, SODIUM SELENATE, VITAMIN K1, VITAMIN D3, VITAMIN B12

By Nature:
Milk, Soy

DRI Coverage

Meets or exceeds 100% DRI for 22 key vitamins and minerals: Adult (+14 years old), 1000 mL

Impact® Peptide 1.5 Unflavored 24 x 250 mL Impact® Peptide 1.5 Unflavored 6 x 1000 mL
HCPCS Code B4153 B4153
NDC-Format Number 43900-0973-99 43900-0973-70
Case UPC 10043900974009 10043900973712
Each UPC 00043900973999 00043900973708
Product Code 4390097400 4390097371

Protein Source

  • Hydrolyzed Casein (Milk)
  • L-Arginine

Fat Source

  • Medium Chain Triglycerides
  • Refined Fish Oil (Anchovy, Sardine)
  • Soybean Oil

Carbohydrate Source

  • Maltodextrin
  • Cornstarch
  • Patients at risk of infection associated with major elective surgery (upper GI, lower GI, bladder, gynecological oncology, head and neck, non-small cell lung cancer, cardiac and hernia)
  • Patients at risk of infection associated with trauma, traumatic brain injury, burns
  • Wounds and pressure injuries (Stages 2, 3, 4, unstageable)
  • Patients at risk of GI intolerance
  • Metabolic stress
  • Volume sensitivity
  • Increased caloric needs
  • Early enteral feeding
  • Transition from TPN

Important Notes:

NOT FOR PARENTERAL USE This product is intended for use under medical supervision. Suitable for use in adults. Not indicated when immune suppression is desired.

  • Lactose intolerance*
  • Gluten-free

Important Notes:

*Not for individuals with galactosemia IMPACT® PEPTIDE 1.5 formula contains milk protein. Not appropriate for individuals with cow’s milk protein allergy.

WATER, MALTODEXTRIN, ENZYMATICALLY HYDROLYZED CASEIN (MILK), MEDIUM CHAIN TRIGLYCERIDES, AND LESS THAN 2% OF L-ARGININE, CORNSTRACH, REFINED FISH OIL (ANCHOVY, SARDINE), SOYBEAN OIL, CITRIC ACID, CALCIUM CITRATE, RNA SALT, MAGNESIUM CHLORIDE, POTASSIUM PHOSPHATE, ASCORBIC ACID, SALT, SOY LECITHIN, SODIUM CITRATE, CHOLINE CHLORIDE, GUAR GUM, XANTHAN GUM, POTASSIUM CITRATE, TAURINE, MAGNESIUM OXIDE, SODIUM ASCORBATE, L-CARNITINE, DL-ALPHA TOCOPHERYL ACETATE, ZINC SULFATE, FERROUS SULFATE, NIACINAMIDE, CALCIUM PANTOTHENATE, MANGANESE SULFATE, COPPER SULFATE, PYRIDOXINE HYDROCHLORIDE, BETA-CAROTENE, THIAMINE MONONITRATE, VITAMIN A PALMITATE, RIBOFLAVIN, FOLIC ACID, BIOTIN, SODIUM MOLYBDATE, CHROMIUM CHLORIDE, POTASSIUM IODIDE, SODIUM SELENATE, VITAMIN K1, VITAMIN D3, VITAMIN B12

By Nature: Milk, Soy

Meets or exceeds 100% DRI for 22 key vitamins and minerals: Adult (+14 years old), 1000 mL

Impact® Peptide 1.5 Unflavored 24 x 250 mL Impact® Peptide 1.5 Unflavored 6 x 1000 mL
HCPCS Code B4153
NDC-Format Number 43900-0973-99
Case UPC 10043900974009
Each UPC 00043900973999
Product Code 4390097400
HCPCS Code B4153
NDC-Format Number 43900-0973-70
Case UPC 10043900973712
Each UPC 00043900973708
Product Code 4390097371

Notes & Disclaimers for Key Benefits (Healthcare Professionals)

  • 1. Drover JW, et al. JACS. 2011; 212:385-399.
  • 2. Waitzberg DL, et al. World J Surg. 2006;30:1592-1604.
  • 3. Atkinson S, et al. Crit Care Med. 1998;26:1164-1172.
  • 4. Yu K et al. JPEN. 2020:44(5):742-767.
  • 5. McClave S, et al. JPEN. 2016;40(2):159-211.
  • 6. Bozeman MC, et al. JHEOR. 2022:9(1):1-10.
  • 7. Rumberger L et al. JPEN 2014. A1835637.
  • 8. EPUAP, NPIAP & PPPIA. Emily Haesler (Ed.). Prevention and Treatment of Pressure Ulcers/Injuries: Quick Reference Guide. 2019.
  • 8. Chow O & Barbul A. Adv Wound Care. 2014;3(1):46-53.